Specifically, the presenter noted that moderate-to-vigorous physical activity tempered one's genetic risk of obesity from up to 42 loci associated with weight in a study of 8,113 adolescents. If you're like me, you probably had a Duh! moment. After all, regular exercise and proper nutrition are key to obtaining & maintaining a healthy weight. So, as I've noted previously in a series of posts, don't just sit there, do something!