I mention this because a meta-analysis was published early online 2 weeks ago in the European Heart Journal concluding that angiotensin-converting enzyme (ACE) inhibitors decreased all-cause mortality by 10% compared to other blood pressure lowering agents. The authors analyzed data from 20 randomized controlled trials including mortality data for which 158,998 participants avg 67yo w/58% men were followed for 4+ years. Interestingly, their cousin class, the AT1 receptor blockers (ARBs) had no effect on mortality. Their only benefit? Less likely to cause the dry ticklish cough associated w/ACE inhibitors.