When I was growing up (not that I don't need to still mature), I used to watch a commercial on TV with the tagline "A mind is a terrible thing to waste". Well, it turns out health-wise that a waist is a terrible thing to mind. Just ask the two-thirds of Americans who are overweight & obese. Weight loss is a multi-billion dollar industry and what appears to be a never-ending saga of woe. But why bother?
So what does this study add to our previous fount of knowledge? Well, it's observational conclusion is in sync (think trend, right?) w/what we've known for quite some time: heart disease occurs more frequently in those who are overweight or obese. But this is just an association. We've never been able to isolate weight from its comorbidities, eg diabetes, dyslipidemia, hypertension, etc. Which is why it was important to toss genetics into the fray in an attempt to demonstrate causality. Regardless, the message is still the same. Eat less, exercise more. Lower your risk of heart disease by getting rid of excess body fat.