In the past, we used the phrase watchful waiting. In other words, we just checked & repeated their PSA at regular intervals looking for an increase beyond some pre-specified level. Nowadays, we think of active surveillance in which the patient undergoes repeat biopsy at regular intervals to demonstrate stability of the neoplasm or progression to high grade disease. Again, I can only imagine the look on the faces of those randomized to placebo now slapping their forehead and exclaiming "I could have had a V8" or at least daily dutasteride to slow down the progression of disease.
back in January when I had first written about it. Upon looking back, I'm glad to say that I'm at least consistent. Whether that's good or bad is open to debate. Sure REDEEM was a randomized controlled trial good for demonstrating cause & effect. However, in this situation, reality isn't so much black & white as it is various shades of gray. It turns out that dutasteride, just like finasteride, can decrease the incidence of prostate cancer but only while increasing the risk of high grade cancer. You'll need to decide for yourself whether less hair loss or improvement in prostate symptoms is worth the potential risk/side effect.